◉ Autoimmune disease

It is estimated that 4.5% of the world population suffer from autoimmune disorders. Over 100 autoimmune diseases have been identified. Among them, type 1 diabetes (T1D) is estimated to afflict as many as 10 million people worldwide. T1D is characterized by an autoimmune destruction of beta cells in patients. Preservation of beta cells is the key to reversing T1D.

Currently, no drugs specific for T1D are clinically available. Anti-diabetic drugs and immunomodulators are commonly used to treat T1D. Pdia4 inhibitor PS-002 can be used to treat T1D and/or other autoimmune disorders.